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Fig. 1 | Journal of Nanobiotechnology

Fig. 1

From: Development of targeted therapy therapeutics to sensitize triple-negative breast cancer chemosensitivity utilizing bacteriophage phi29 derived packaging RNA

Fig. 1

Characterizations of pRNA-EGFRapt-siXBP1 NPs. a Scheme of pRNA-EGFRapt-siXBP1NPs. b Native PAGE showing stepwise highly efficient assembly of the NPs. c Atomic force microscopy (AFM) images of pRNA nanoparticles. d Stability analyze by 8% native PAGE gel electrophoresis after RNase A and10% FBS-supplemented DMEM medium treatments for the indicated time at 37 °C. e Tm value of pRNA-EGFRapt-siXBP1 NPs determined by SYBR Green assay. f DLS measurements showing the hydrodynamic size. g Zeta potential

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