Table 1 Characterization of TAT-TMP-NPs with different dosage
TMP (mg) | Particle size (nm) | Polydispersity index | Zeta potential (mV) | Drug loading (%) | Entrapment efficiency (%) |
|---|---|---|---|---|---|
0 | 79.07 ± 0.36 | 0.26 ± 0.01 | − 28.50 ± 5.16 | – | – |
10 | 96.04 ± 2.77 | 0.25 ± 0.03 | − 22.30 ± 0.56 | 4.70 ± 0.06 | 40.50 ± 1.28 |
20 | 143.27 ± 0.12 | 0.25 ± 0.02 | − 23.27 ± 0.65 | 4.90 ± 0.51 | 62.04 ± 0.08 |
30 | 163.93 ± 0.38 | 0.18 ± 0.01 | − 26.10 ± 4.55 | 8.02 ± 0.12 | 77.27 ± 1.99 |
40 | 258.57 ± 2.60 | 0.41 ± 0.02 | − 20.07 ± 1.01 | 7.33 ± 1.10 | 75.70 ± 6.01 |