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Fig. 6 | Journal of Nanobiotechnology

Fig. 6

From: Restorative biodegradable two-layered hybrid microneedles for melanoma photothermal/chemo co-therapy and wound healing

Fig. 6

A Time scheme of animal experiment. B NIR thermal images of mice in G2, G5 and G6 with 808 nm laser irradiation (0.75 W/cm2) for 5 min. C Temperature changes of tumor site within 5 min. D Tumor volume and F body weight of mice for 14 days after treatment. E Photograph of detached tumors in each group and G their weights on day 14. G1: Control; G2: HA MNs; G3: Cur NDs/HA MNs; G4: Cur NDs/IR820/HA MNs; G5: IR820 MNs + laser; G6: Cur NDs/IR820/HA MNs + laser. *p < 0.05, **p < 0.01, ***p < 0.001

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