Fig. 4
![Fig. 4](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12951-022-01543-1/MediaObjects/12951_2022_1543_Fig4_HTML.png)
MBCDs induced mice liver oxidative stress. a Volcano plot of differential gene expression. b Cluster map of differential gene expression. c Top 30 GO terms. (n = 3). d The activities of total SOD (T-SOD) and glutathione (GSH) in the serum and the liver. The levels of malondialdehyde (MDA) in the serum and the liver. e, f Oxidative stress-related genes were validated by RT–qPCR. g Protein expression of Nrf2/HO-1 pathway. *p < 0.05 for L vs. C group, #p < 0.05 for H vs. C group, ##p < 0.01 for H vs.C group, ###p < 0.001 for H vs. C group. Results are the mean ± SE (n = 8)