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Fig. 4 | Journal of Nanobiotechnology

Fig. 4

From: A novel multifunctional microneedle patch for synergistic photothermal- gas therapy against maxillofacial malignant melanoma and associated skin defects

Fig. 4

The biocompatibility of MNs. a Cell viability of BMSCs after culturing with SCMC@MNs, SNP-Fe@MNs loading 0.01, 0.03, 0.05, 0.10, and 0.15 g mL−1 SNP and Fe2+ for 24 h and 48 h, respectively. b CLSM images of HUVECs stained with the Calcein-AM/PI Kit from the Control, SCMC@MNs, SNP-Fe@MNs-NO(−), SNP-Fe@MNs-NO(+) groups. c Relative proportion of living and dead cells (n = 5. *P < 0.05; **P < 0.01; ***P < 0.0001)

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