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Fig. 2 | Journal of Nanobiotechnology

Fig. 2

From: An exosomal strategy for targeting cancer-associated fibroblasts mediated tumors desmoplastic microenvironments

Fig. 2

Schematic illustration of engineered exosomes targeting CAFs mediated desmoplastic microenvironments to exert theranostic potential on desmoplastic tumors models. After injection, antigen and theranostic agents-loaded exosomes can target CAFs mediated desmoplastic microenvironments to exert theranostic potential via stimulating the activation of CD8+T cell, removing ECM, inactivating CAFs, inhibiting the signal transduction of CAF-tumor cells and CAF-immune cells crosstalk, and imaging in vivo

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Journal of Nanobiotechnology

ISSN: 1477-3155

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