Fig. 1

Characterisation of Hm@TSA/As-MOF. The particle size distribution (A) and zeta potential (B) of Fe₃O₄, MOF, TSA/As-MOF and Hm@TSA/As-MOF were determined via DLS (n = 3). Representative images of SEM (C) (scale bar = 200 nm) and TEM (D) (scale bar = 50 nm) of MOF and Hm@TSA/As-MOF are shown. The co-localization of Hm and TSA/As-MOF in Hm@TSA/As-MOF was demonstrated by laser confocal microscopy (E). The protein profile of Hm@TSA/As-MOF was examined via SDS-PAGE (F). The responsiveness of MOF, TSA/As-MOF and Hm@TSA/As-MOF to magnetic fields was tested using VSM (G). The pore characteristics of Hm@TSA/As-MOF was observed by the curves of nitrogen adsorption and desorption (H). The TGA was tested in a N₂ environment (I). The crystal structure of Fe₃O₄, MIL-100 (Fe), MOF, TSA/As, TSA/As-MOF and Hm@TSA/As-MOF was examined via XRD (J). The UV (K) and FTIR (L) spectras of TSA/As-MOF and Hm@TSA/As-MOF are shown. The release profiles of TSA and As at different conditions (pH 7.4, pH 6.4 and 10-mM GSH) (n = 3) (M) are shown. Data are expressed as the mean ± SD