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Fig. 3 | Journal of Nanobiotechnology

Fig. 3

From: Homologous-magnetic dual-targeted metal-organic framework to improve the Anti-hepatocellular carcinoma efficacy of PD-1 inhibitor

Fig. 3

Homologous targeting and immune escape abilities of Hm@TSA/As-MOF. The homologous targeting between Hm@C6-MOF and H22, HepG2 and CT26 cells was examined via fluorescence microscopy (A) (scale bar = 50 μm) and flow cytometry (B, C). The homologous targeting between Hm@C6-MOF and H22 and HSC cells was examined via fluorescence microscopy (D) (scale bar = 50 μm) and flow cytometry (E, F). The phagocytoses of C6-MOF and Hm@C6-MOF by Raw264.7 cells were examined via fluorescence microscopy (G) (scale bar = 50 μm) and flow cytometry (H, I). The phagocytoses of C6-MOF and Hm@C6-MOF by macrophages in normal mice (J, K) and HCC mice (L, M) were examined via flow cytometry. Data are expressed as the mean ± SD (***, p < 0.001; two-tailed Student’s t-test)

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